Every organization needs a rallying point. Imagine a health care system oriented toward healing in every aspect of safety, care, operations, physical environment, and strategic planning. Cape Coral Hospital drove improved business outcomes through the lens of Samueli Institute’s Optimal Healing Environment (OHE) framework using lean as its management system. The results showed improvements in safety and quality, financial performance, patient experience, employee engagement, community support, and philanthropy. Working within the OHE framework, hospital leadership was able to drive decisions to enhance the cultural transformation.