An interprofessional care team model (ICTM) is essential to providing safe, effective and high-quality health care. The development of an ICTM was a pivotal focus in the Children’s Hospital of Richmond at VCU’s (CHoR) Wonder Tower. From the project’s beginning, the clinical team was engaged, with an interprofessional mindset, to develop the building. Current state analysis identified several barriers to ICTM. Future state mapping developed targets for process improvement. Design development and intent documents highlighted the ICTM spaces and detailed the expected collaboration and experience within the space. Detailed operational maps focused on shifting the cultural mindset, incorporating decisions made along the way, including staffing models and technology. Integrating clinical perspectives throughout the CHoR approach resulted design and operational plans intended to shift the care paradigm from one of siloed to teams to an interprofessional care team model, resulting in increased communication, collaboration, experience and satisfaction, and improved clinical outcomes.